Nexium (esomeprazole) is a highly-efficient medicine intended for the treatment of GERD (gastroesophageal reflux disease) and other conditions caused by the excessive production of stomach acid. Take this medicine at least an hour before having a meal, at the same time every day. If your health care provider gave other recommendations concerning your diet – observe those as well to make sure your treatment is efficient and you are benefitting from it. If you missed a dose of Nexium – you can take it as soon as you remember unless it’s time for the next one. In that case you can skip the dose missed and carry on with your treatment. Never take a double dose, as this is not going to make Nexium more efficient and can lead to an overdose. Although an overdose of Nexium is not expected to produce life-threatening effects, you still need to seek emergency medical help for yourself or another person who overdosed. the following symptoms indicate an overdose: confusion, dry mouth, blurred vision, headache, shortness of breath, sweating, nausea, drowsiness, flushing, and loss of coordination. You should never combine this drug with such medications as iron, clopidogrel, blood thinners, HIV or AIDS medications, diazepam, digoxin, or ketoconazole, as interactions have been reported. Your doctor is supposed to know about any health conditions you have (such as liver disease of heart disease), as they may affect the dose you are prescribed, and any prescription or over-the-counter medications you are already taking or intend to take along with Nexium. Side effects are not too common, and even if they do take place – you are unlikely to suffer from their severity of have them for several days. Such side effects as headache, constipation, dry mouth, nausea, stomach pain, gas, and diarrhea are supposed to be reported to your doctor only if they get bothersome and do not go away for a long time. Tell your health care provider if you develop any other side effects that seem strange. This is possible and cannot be foreseen as every person may have a slightly different reaction to Nexium treatment. If you think you need a dose adjustment – contact your doctor to see if this is something that will not cause any health effects you would rather avoid. In general, you should never hesitate to ask your doctor any questions you may have to make sure your treatment is efficient and you are benefitting from the dose prescribed.